The process is still complex and risky, and it is not recommended in the long term because it involves installing a kernel changed, but have already managed to get Mac OS X 10.6 Snow Leopard to work on Intel's new Sandy Bridge chips.
Anyone willing to venture out will already find instructions on how to repeat the feat, and even a forum covering only the installation of Apple's desktop operating system on the new Intel line was created at tonymacX86. Only, until Ma decides to officially adopt these processors on its machines (something that could mean ?Goodbye, NVIDIA GPUs?), the compatibility between software and hardware will depend on workarounds that definitely do not match with a computer on which you depend to work from Monday to Friday.
If you want to play, however, the biggest obstacle for now is going to be getting a Sandy Bridge processor itself and making sure that it ?doesn't die in the end?.